环境与化学工程学院
通讯地址：江苏省镇江市丹徒区竞技宝登录入口长山校区
个人邮箱：juansong@just.edu.cn
邮政编码：
办公地点：环境与化学工程楼201室
传真：
宋娟，竞技宝登录入口，讲师，硕士研究生导师。2019年博士毕业于南京大学化学化工学院，导师陈洪渊院士，徐静娟教授。随后以特任副研究员身份在南京大学化学化工学院从事科研工作3年。2023年2月入职于竞技宝登录入口。
目前主持国家自然科学青年基金项目（2020-2023）一项，企业横向（2023-2025）1项，竞技宝登录入口人才启动基金项目（2023-2025）一项。
2020年入选江苏省“双创博士”，2023年入选江苏省科技副总。
主要从事单细胞、单分子相关的电化学和电生理交叉应用领域的研究。以具有电化学限域效应的石英纳米孔道作为分析工具，发展了纳米孔道单分子电化学检测技术，实时动态捕获单分子，单颗粒以及单细胞等功能变化信息，解析单个生物分子之间的相互作用特性。目前已在包括Angewandte Chemie International Edition，ACS Nano，Nano Letters等权威期刊上发表论文10余篇。
（1）纳米材料合成及生物标志物分析应用
（2）单细胞分析
（3）微纳尺度生物分析
代表性文章：
1. Zhou Xueyan, Song Juan*, Zhu Qi, Xu Meifeng, Shen Wei, Lee Hian Kee*, Tang Sheng*, Target-Triggered DNA Hydrogel Gating with Nanoconfinement Effect in Micropipettes for Antibiotic Resistance Gene Detection. Analytical Chemistry, 2025, 97 (11), 6118–6125.
2. Zhang Xian, Wu Zeng-Qiang, Zheng You-Wei, Song Juan*, Zhao Wei-Wei*, Jing-Juan Xu*, Bridging Ionic Current Rectification and Resistive-Pulse Sensing for Reliable Wide-Linearity Detection. Analytical Chemistry, 2024, 96 (16), 6444–6449.
3. Zhang Xian, Song Juan*, Li Zheng, Zheng You-Wei, ZhaoWei-Wei*, Chen Hong-Yuan, Jing-Juan Xu*, θ-Nanopipette for Single-Cell Resistive-Pulse Profiling of DNA Repair Proteins Accompanied by Drug Evaluation. Nano Letters, 2023, 23, 8249-8255.
4. Wang Jin, Song Juan, Zhang Xian, Wang Shu-Min, Kang Bin, Li Xiang-Ling, Chen Hong-Yuan, Xu Jing-Juan. DNA-Programed Plasmon Rulers Decrypt Single-Receptor Dimerization on Cell Membrane. J. Am. Chem. Soc. 2023, 145, 2, 1273–1284
5. Zhang Xian,Dan Luo, You-Wei Zheng, Song Juan*, Xu Jing-Juan*, Chen Hong-Yuan, Translocation of Functional DNA Nanostructures Through an Ultrasmall Nanopipette: Toward Single Protein Molecule Detection with Superior Signal-to-Noise Ratio. ACS Nano. 2022, 16, 15108–15114.
6. Li Xiao-Qiong, Song Juan*, Xu Jing-Juan*, Chen Hong-Yuan, Near-Infrared Photothermally Activated DNA nanotweezers for Imaging ATP in Living Cells. Chem. Commun. 2022, 58, 8210-8213.
7. Song Juan, Pan Jian-Bin, Zhao Wei *, Chen Hong-Yuan, Xu Jing-Juan*, Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways. Chem. Commun.2020, 56, 6118—6121.
8. Song Juan, Xu Cong-Hui, Zhao Wei*, Xu Jing-Juan*, and Chen Hong-Yuan. Ultrasmall nanopipette: toward continuous monitoring of redox metabolism at subcellular level. Angew. Chem. Int. Ed.2018, 57, 13226 –13230.
9. Gu Yu, SongJuan, Li Mei-Xing, Zhang Ting-Ting, Zhao Wei, Xu Jing-Juan*, Liu Maili and Chen Hong-Yuan. Ultrasensitive microRNA assay via surface plasmon resonance responses of Au@Ag nanorods etching. Anal. Chem. 2017, 89, 10585-10591.
10. Song Juan, Wu Fangying*, Colorimetric detection of thiocyanate based on anti-aggregation of gold nanoparticles in the presence of cetyltrimethyl ammonium bromide, Sens. Actuator B-Chem. 2016, 222: 790-796.
11. Song Juan, Wu Fangying*, Wan Yiqun, Ma Lihua, Colorimetric detection of melamine in pretreated milk using silver, Food Control, 2015, 50: 356-361.
12. Song Juan, Wu Fangying*, Wan Yi-Qun, Ma Li-Hua, Ultrasensitive turn-on fluorescent detection of trace thiocyanate based, Talanta, 2015, 132: 619-624.
13. Song, Juan, Wu Fangying*, Wan Yiqun, Ma Li-Hua, Visual test for melamine using silver nanoparticles modified with, Microchimica Acta, 2014, 181 (11-12): 1267-1274.
主持项目：
（1）基于仿生细胞模型研究金纳米棒的光热作用对跨膜蛋白转运功能的影响，国家自然科学青年基金项目，2020-2023，主持（结题）；
（2）生物样品中超灵敏蛋白检测方法研究，企业横向项目，2023-2025，主持（在研）；
（3）竞技宝登录入口人才启动基金，2023-2026，主持（在研）。
代表性文章：
1. Zhou Xueyan, Song Juan*, Zhu Qi, Xu Meifeng, Shen Wei, Lee Hian Kee*, Tang Sheng*, Target-Triggered DNA Hydrogel Gating with Nanoconfinement Effect in Micropipettes for Antibiotic Resistance Gene Detection. Analytical Chemistry, 2025, 97 (11), 6118–6125.
2. Zhang Xian, Wu Zeng-Qiang, Zheng You-Wei, Song Juan*, Zhao Wei-Wei*, Jing-Juan Xu*, Bridging Ionic Current Rectification and Resistive-Pulse Sensing for Reliable Wide-Linearity Detection. Analytical Chemistry, 2024, 96 (16), 6444–6449.
3. Zhang Xian, Song Juan*, Li Zheng, Zheng You-Wei, ZhaoWei-Wei*, Chen Hong-Yuan, Jing-Juan Xu*, θ-Nanopipette for Single-Cell Resistive-Pulse Profiling of DNA Repair Proteins Accompanied by Drug Evaluation. Nano Letters, 2023, 23, 8249-8255.
4. Wang Jin, Song Juan, Zhang Xian, Wang Shu-Min, Kang Bin, Li Xiang-Ling, Chen Hong-Yuan, Xu Jing-Juan. DNA-Programed Plasmon Rulers Decrypt Single-Receptor Dimerization on Cell Membrane. J. Am. Chem. Soc. 2023, 145, 2, 1273–1284
5. Zhang Xian,Dan Luo, You-Wei Zheng, Song Juan*, Xu Jing-Juan*, Chen Hong-Yuan, Translocation of Functional DNA Nanostructures Through an Ultrasmall Nanopipette: Toward Single Protein Molecule Detection with Superior Signal-to-Noise Ratio. ACS Nano. 2022, 16, 15108–15114.
6. Li Xiao-Qiong, Song Juan*, Xu Jing-Juan*, Chen Hong-Yuan, Near-Infrared Photothermally Activated DNA nanotweezers for Imaging ATP in Living Cells. Chem. Commun. 2022, 58, 8210-8213.
7. Song Juan, Pan Jian-Bin, Zhao Wei *, Chen Hong-Yuan, Xu Jing-Juan*, Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways. Chem. Commun.2020, 56, 6118—6121.
8. Song Juan, Xu Cong-Hui, Zhao Wei*, Xu Jing-Juan*, and Chen Hong-Yuan. Ultrasmall nanopipette: toward continuous monitoring of redox metabolism at subcellular level. Angew. Chem. Int. Ed.2018, 57, 13226 –13230.
9. Gu Yu, SongJuan, Li Mei-Xing, Zhang Ting-Ting, Zhao Wei, Xu Jing-Juan*, Liu Maili and Chen Hong-Yuan. Ultrasensitive microRNA assay via surface plasmon resonance responses of Au@Ag nanorods etching. Anal. Chem. 2017, 89, 10585-10591.
10. Song Juan, Wu Fangying*, Colorimetric detection of thiocyanate based on anti-aggregation of gold nanoparticles in the presence of cetyltrimethyl ammonium bromide, Sens. Actuator B-Chem. 2016, 222: 790-796.
11. Song Juan, Wu Fangying*, Wan Yiqun, Ma Lihua, Colorimetric detection of melamine in pretreated milk using silver, Food Control, 2015, 50: 356-361.
12. Song Juan, Wu Fangying*, Wan Yi-Qun, Ma Li-Hua, Ultrasensitive turn-on fluorescent detection of trace thiocyanate based, Talanta, 2015, 132: 619-624.
13. Song, Juan, Wu Fangying*, Wan Yiqun, Ma Li-Hua, Visual test for melamine using silver nanoparticles modified with, Microchimica Acta, 2014, 181 (11-12): 1267-1274.
主持项目：
（1）基于仿生细胞模型研究金纳米棒的光热作用对跨膜蛋白转运功能的影响，国家自然科学青年基金项目，2020-2023，主持（结题）；
（2）生物样品中超灵敏蛋白检测方法研究，企业横向项目，2023-2025，主持（在研）；
（3）竞技宝登录入口人才启动基金，2023-2026，主持（在研）。
代表性文章：
1. Zhou Xueyan, Song Juan*, Zhu Qi, Xu Meifeng, Shen Wei, Lee Hian Kee*, Tang Sheng*, Target-Triggered DNA Hydrogel Gating with Nanoconfinement Effect in Micropipettes for Antibiotic Resistance Gene Detection. Analytical Chemistry, 2025, 97 (11), 6118–6125.
2. Zhang Xian, Wu Zeng-Qiang, Zheng You-Wei, Song Juan*, Zhao Wei-Wei*, Jing-Juan Xu*, Bridging Ionic Current Rectification and Resistive-Pulse Sensing for Reliable Wide-Linearity Detection. Analytical Chemistry, 2024, 96 (16), 6444–6449.
3. Zhang Xian, Song Juan*, Li Zheng, Zheng You-Wei, ZhaoWei-Wei*, Chen Hong-Yuan, Jing-Juan Xu*, θ-Nanopipette for Single-Cell Resistive-Pulse Profiling of DNA Repair Proteins Accompanied by Drug Evaluation. Nano Letters, 2023, 23, 8249-8255.
4. Wang Jin, Song Juan, Zhang Xian, Wang Shu-Min, Kang Bin, Li Xiang-Ling, Chen Hong-Yuan, Xu Jing-Juan. DNA-Programed Plasmon Rulers Decrypt Single-Receptor Dimerization on Cell Membrane. J. Am. Chem. Soc. 2023, 145, 2, 1273–1284
5. Zhang Xian,Dan Luo, You-Wei Zheng, Song Juan*, Xu Jing-Juan*, Chen Hong-Yuan, Translocation of Functional DNA Nanostructures Through an Ultrasmall Nanopipette: Toward Single Protein Molecule Detection with Superior Signal-to-Noise Ratio. ACS Nano. 2022, 16, 15108–15114.
6. Li Xiao-Qiong, Song Juan*, Xu Jing-Juan*, Chen Hong-Yuan, Near-Infrared Photothermally Activated DNA nanotweezers for Imaging ATP in Living Cells. Chem. Commun. 2022, 58, 8210-8213.
7. Song Juan, Pan Jian-Bin, Zhao Wei *, Chen Hong-Yuan, Xu Jing-Juan*, Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways. Chem. Commun.2020, 56, 6118—6121.
8. Song Juan, Xu Cong-Hui, Zhao Wei*, Xu Jing-Juan*, and Chen Hong-Yuan. Ultrasmall nanopipette: toward continuous monitoring of redox metabolism at subcellular level. Angew. Chem. Int. Ed.2018, 57, 13226 –13230.
9. Gu Yu, SongJuan, Li Mei-Xing, Zhang Ting-Ting, Zhao Wei, Xu Jing-Juan*, Liu Maili and Chen Hong-Yuan. Ultrasensitive microRNA assay via surface plasmon resonance responses of Au@Ag nanorods etching. Anal. Chem. 2017, 89, 10585-10591.
10. Song Juan, Wu Fangying*, Colorimetric detection of thiocyanate based on anti-aggregation of gold nanoparticles in the presence of cetyltrimethyl ammonium bromide, Sens. Actuator B-Chem. 2016, 222: 790-796.
11. Song Juan, Wu Fangying*, Wan Yiqun, Ma Lihua, Colorimetric detection of melamine in pretreated milk using silver, Food Control, 2015, 50: 356-361.
12. Song Juan, Wu Fangying*, Wan Yi-Qun, Ma Li-Hua, Ultrasensitive turn-on fluorescent detection of trace thiocyanate based, Talanta, 2015, 132: 619-624.
13. Song, Juan, Wu Fangying*, Wan Yiqun, Ma Li-Hua, Visual test for melamine using silver nanoparticles modified with, Microchimica Acta, 2014, 181 (11-12): 1267-1274.
主持项目：
（1）基于仿生细胞模型研究金纳米棒的光热作用对跨膜蛋白转运功能的影响，国家自然科学青年基金项目，2020-2023，主持（结题）；
（2）生物样品中超灵敏蛋白检测方法研究，企业横向项目，2023-2025，主持（在研）；
（3）竞技宝登录入口人才启动基金，2023-2026，主持（在研）。
学校地址：江苏省镇江市丹徒区长晖路666号
邮编：212100
版权所有©2013-2022 竞技宝登录入口 苏ICP备05063164号
